> proposed digestive condition where the intestinal lining allows bacteria and toxins into the bloodstream.
-> digestive enzymes in the stomach and small intestine break down nutrients in food and drink into smaller molecules that the body uses for energy, growth, and repair.
-> tight openings in the intestinal walls allow water and nutrients to pass through into the bloodstream while keeping harmful substances inside. The rate of this passing is known as intestinal permeability (IP).
-> a chronic increase in IP (LGS), allows food particles, bacteria, and toxins to enter directly into the bloodstream.
-> intestines are also home to a wide range of bacteria called gut microbiota. These bacteria aid digestion, protect the intestinal wall, and support immune function.
-> imbalanced gut microbiota can trigger the body’s immune response, causing inflammation and increased IP.
The link between IP and other health conditions
A chronic increase in IP may contribute to several health conditions, including:
chronic liver disease
food allergies and sensitivities
However, a 2015 review article suggests that increased IP may contribute to inflammatory bowel disease (IBD). A separate 2019 review shows evidence of IP occurring before the onset of type 1 diabetes.
-> Scientists have also been investigating the gut-brain axis. This is the relationship between the GI tract and the brain.
A 2017 review suggests that leaky gut may contribute to mental health conditions, such as anxiety and depression.
Adapted from: www.medicalnewstoday.com/articles/326117#what-is-it
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